ChemicalBook >> CAS DataBase List >>2-Aminothiazole
2-Aminothiazole
- CAS No.
- 96-50-4
- Chemical Name:
- 2-Aminothiazole
- Synonyms
- Aminothiazole;1,3-Thiazol-2-amine;aminothiazol;2-THIAZOLAMINE;Abadol;cp1585;BASEDOL;RP 2921;ABADOLE;AKOS 204-05
- CBNumber:
- CB5215834
- Molecular Formula:
- C3H4N2S
- Molecular Weight:
- 100.14
- MDL Number:
- MFCD00005325
- MOL File:
- 96-50-4.mol
- MSDS File:
- SDS
Last updated:2024-04-10 13:06:19
| Melting point | 91-93 °C (lit.) |
|---|---|
| Boiling point | 117 °C (15.002 mmHg) |
| Density | 1.241 (estimate) |
| vapor pressure | <1 hPa (20 °C) |
| refractive index | 1.5300 (estimate) |
| Flash point | 117°C/15mm |
| storage temp. | Store below +30°C. |
| solubility | 1 M HCl: soluble50mg/mL, clear (dark yellow-brown) |
| pka | 5.36(at 20℃) |
| form | Crystalline Powder, Grains, Lumps or Flakes |
| color | Brown |
| PH | 9.6 (100g/l, H2O, 20℃) |
| Water Solubility | 100 g/L (20 ºC) |
| Merck | 14,479 |
| BRN | 105738 |
| InChIKey | RAIPHJJURHTUIC-UHFFFAOYSA-N |
| LogP | 0.380 |
| CAS DataBase Reference | 96-50-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 5K8WKN668K |
| NIST Chemistry Reference | 2-Aminothiazole(96-50-4) |
| EPA Substance Registry System | 2-Aminothiazole (96-50-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36-36/37-20/21/22 | |||||||||
| Safety Statements | 26-36/37-39-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XJ2100000 | |||||||||
| F | 8-9 | |||||||||
| Autoignition Temperature | 600 °C | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29341000 | |||||||||
| Toxicity | LD50 orally in Rabbit: 480 mg/kg | |||||||||
| NFPA 704 |
|
2-Aminothiazole price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.01272 | 2-Aminothiazole for synthesis | 96-50-4 | 100g | $41.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 123129 | 2-Aminothiazole 97% | 96-50-4 | 5g | $30.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.01272 | 2-Aminothiazole for synthesis | 96-50-4 | 500g | $152 | 2024-03-01 | Buy |
| Sigma-Aldrich | 123129 | 2-Aminothiazole 97% | 96-50-4 | 100g | $57.1 | 2024-03-01 | Buy |
| TCI Chemical | A0633 | 2-Aminothiazole >98.0%(T) | 96-50-4 | 25g | $22 | 2024-03-01 | Buy |
2-Aminothiazole Chemical Properties,Uses,Production
Chemical Properties
brown crystalline powder, grains, lumps or flakes
Uses
Usually used in the synthesis of 2-aminothiazole-modified silica gel，and aslo used in Ulmann coupling with 2-chlorobenzoic acids mediated by ultrasonic irradiation.
Uses
antithyroid agent
Uses
2-Aminothiazole is a heterocyclic amine and is the beginning reagent for the synthesis of many pharmaceutical and agricultural related compounds.
Definition
ChEBI: A primary amino compound that is 1,3-thiazole substituted by an amino group at position 2.
Synthesis Reference(s)
Journal of the American Chemical Society, 76, p. 693, 1954 DOI: 10.1021/ja01632a016
General Description
Light brown crystals or brown granular solid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Aminothiazole reacts violently when nitrated with nitric or nitric-sulfuric acids. 2-Aminothiazole is also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides.
Fire Hazard
Flash point data for 2-Aminothiazole are not available; however, 2-Aminothiazole is probably combustible.
Biochem/physiol Actions
2-Aminothiazoles are potent cyclin-dependent kinase 5 inhibitors and are therapeutic agents for the treatment of Alzheimer′s disease and other neurodegenerative disorders.
Safety Profile
Poison by ingestion andintraperitoneal routes. Mutation data reported.Spontaneous ignition occurs at 100°. Mixtures with nitricacid or nitric acid + sulfuric acid explode on heating.Incompatible with HNO3 and H2SO4. When heated todecomposition it emi
Purification Methods
It crystallises from pet ether (b 100-120o), or EtOH. [Beilstein 27 III/IV 4574.]
2-Aminothiazole Preparation Products And Raw materials
Raw materials
Preparation Products
2-CHLORO-5-NITROTHIAZOLE
ethyl 2-(2-aminothiazol-5-ylthio)acetate
2-Amino-((1-carboxy-1-methyl ethoxy)imino)-4-thiazoleacetic acid
Cationic Violet 3BL
3-(-Hydroxyphenethyl)-2-imino thiazolidine
BASIC RED 29
1,3-Thiazole-2-carbaldehyde
2-Amino-5-nitrothiazole
2-Amino-5-bromothiazole
2-Amino-5-bromothiazole monohydrobromide
1of4
Global( 592)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 7433 | 58 |
| Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 | sales@qinmuchem.com | China | 1009 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18451 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12471 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18229 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15957 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
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View Lastest Price from 2-Aminothiazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-17 | 2-Aminothiazole
96-50-4
|
US $0.00 / Kg/Drum | 1ASSAYS | 99% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2024-04-10 | 2-Aminothiazole
96-50-4
|
US $18.00 / kg | 1kg | 99.9% | 50000tons | Wuhan Boyuan Import & Export Co., LTD | |
 |
2024-03-29 | 2-Aminothiazole
96-50-4
|
US $6.00-0.20 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 2-Aminothiazole
96-50-4
- US $0.00 / Kg/Drum
- 99%
- Jinan Finer Chemical Co., Ltd
-
- 2-Aminothiazole
96-50-4
- US $18.00 / kg
- 99.9%
- Wuhan Boyuan Import & Export Co., LTD
-
- 2-Aminothiazole
96-50-4
- US $6.00-0.20 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
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1,3-Thiazol-2-amine
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SCNH2NCHCH
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H2NC3H2NS
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